W BIAŁYMSTOKU
Proszę używać tego identyfikatora do cytowań lub wstaw link do tej pozycji:
http://hdl.handle.net/11320/18169| Tytuł: | The Equilibria of Diosgenin–Phosphatidylcholine and Diosgenin–Cholesterol in Monolayers at the Air/Water Interface |
| Autorzy: | Janicka, Katarzyna Jastrzębska, Izabella Petelska, Aneta Dorota |
| Słowa kluczowe: | Diosgenin Phosphatidylcholine Cholesterol Complex formation equilibria Monolayer Langmuir trough |
| Data wydania: | 2016 |
| Data dodania: | 4-kwi-2025 |
| Wydawca: | Springer |
| Źródło: | The Journal of Membrane Biology, 2016, Vol. 249, s. 585–590 |
| Abstrakt: | Diosgenin (Dio) has shown many treatment properties, but the most important property is cytotoxic activity in cancer cells. In this study, we investigated monolayers of Dio, cholesterol (Ch), and phosphatidylcholine (PC) at the air/water interface. The measurements were carried with a Langmuir Teflon trough and a Nima 9000 tensiometer program. The surface tension values of pure and mixed monolayers were used to calculate p–A isotherms and determine molecular surface areas. We were able to demonstrate the formation of complexes between Dio and PC and Dio and Ch molecules also. We considered the equilibrium between individual components and the formed complexes. In addition, we established that diosgenin and the lipids formed highly stable 1:1 complexes. |
| Afiliacja: | Katarzyna Janicka - Institute of Chemistry, University of Bialystok Izabella Jastrzębska - Institute of Chemistry, University of Bialystok Aneta Dorota Petelska - Institute of Chemistry, University of Bialystok |
| E-mail: | Aneta Dorota Petelska: aneta@uwb.edu.pl |
| URI: | http://hdl.handle.net/11320/18169 |
| DOI: | 10.1007/s00232-016-9914-1 |
| ISSN: | 0022-2631 |
| e-ISSN: | 1432-1424 |
| Typ Dokumentu: | Article |
| metadata.dc.rights.uri: | http://creativecommons.org/licenses/by/4.0/ |
| Właściciel praw: | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| Występuje w kolekcji(ach): | Artykuły naukowe (WChem) |
Pliki w tej pozycji:
| Plik | Opis | Rozmiar | Format | |
|---|---|---|---|---|
| K_Janicka_I_Jastrzebska_A_D_Petelska_The_Equilibria_of_Diosgenin_Phosphatidylcholine.pdf | 595,33 kB | Adobe PDF | Otwórz |
Pozycja ta dostępna jest na podstawie licencji Licencja Creative Commons CCL
