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dc.contributor.authorJanicka, Katarzyna-
dc.contributor.authorJastrzębska, Izabella-
dc.contributor.authorPetelska, Aneta Dorota-
dc.date.accessioned2025-04-04T09:59:03Z-
dc.date.available2025-04-04T09:59:03Z-
dc.date.issued2016-
dc.identifier.citationThe Journal of Membrane Biology, 2016, Vol. 249, s. 585–590pl
dc.identifier.issn0022-2631-
dc.identifier.urihttp://hdl.handle.net/11320/18169-
dc.description.abstractDiosgenin (Dio) has shown many treatment properties, but the most important property is cytotoxic activity in cancer cells. In this study, we investigated monolayers of Dio, cholesterol (Ch), and phosphatidylcholine (PC) at the air/water interface. The measurements were carried with a Langmuir Teflon trough and a Nima 9000 tensiometer program. The surface tension values of pure and mixed monolayers were used to calculate p–A isotherms and determine molecular surface areas. We were able to demonstrate the formation of complexes between Dio and PC and Dio and Ch molecules also. We considered the equilibrium between individual components and the formed complexes. In addition, we established that diosgenin and the lipids formed highly stable 1:1 complexes.pl
dc.language.isoenpl
dc.publisherSpringer-
dc.rightsUznanie autorstwa 4.0 Międzynarodowe*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectDiosgeninpl
dc.subjectPhosphatidylcholinepl
dc.subjectCholesterolpl
dc.subjectComplex formation equilibriapl
dc.subjectMonolayerpl
dc.subjectLangmuir troughpl
dc.titleThe Equilibria of Diosgenin–Phosphatidylcholine and Diosgenin–Cholesterol in Monolayers at the Air/Water Interfacepl
dc.typeArticlepl
dc.rights.holderThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.pl
dc.identifier.doi10.1007/s00232-016-9914-1-
dc.description.EmailAneta Dorota Petelska: aneta@uwb.edu.plpl
dc.description.AffiliationKatarzyna Janicka - Institute of Chemistry, University of Bialystokpl
dc.description.AffiliationIzabella Jastrzębska - Institute of Chemistry, University of Bialystokpl
dc.description.AffiliationAneta Dorota Petelska - Institute of Chemistry, University of Bialystokpl
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dc.identifier.eissn1432-1424-
dc.description.volume249pl
dc.description.firstpage585pl
dc.description.lastpage590pl
dc.identifier.citation2The Journal of Membrane Biologypl
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