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    • Proszę używać tego identyfikatora do cytowań lub wstaw link do tej pozycji: http://hdl.handle.net/11320/16598
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    Pole DCWartośćJęzyk
    dc.contributor.authorNiemirowicz-Laskowska, Katarzyna-
    dc.contributor.authorMystkowska, Joanna-
    dc.contributor.authorŁysik, Dawid-
    dc.contributor.authorChmielewska, Sylwia-
    dc.contributor.authorTokajuk, Grażyna-
    dc.contributor.authorMisztalewska-Turkowicz, Iwona-
    dc.contributor.authorWilczewska, Agnieszka Z.-
    dc.contributor.authorBucki, Robert-
    dc.date.accessioned2024-06-03T09:48:58Z-
    dc.date.available2024-06-03T09:48:58Z-
    dc.date.issued2020-
    dc.identifier.citationInternational Journal of Molecular Sciences, Vol. 21, Issue 6 (2020), p. 1-17pl
    dc.identifier.issn1422-0067-
    dc.identifier.urihttp://hdl.handle.net/11320/16598-
    dc.description.abstractSaliva plays a crucial role in oral cavity. In addition to its buffering and moisturizing properties, saliva fulfills many biofunctional requirements, including antibacterial activity that is essential to assure proper oral microbiota growth. Due to numerous extra- and intra-systemic factors, there are many disorders of its secretion, leading to oral dryness. Saliva substitutes used in such situations must meet many demands. This study was design to evaluate the effect of core-shell magnetic nanoparticles (MNPs) adding (gold-coated and aminosilane-coated nanoparticles NPs) on antimicrobial (microorganism adhesion, biofilm formation), rheological (viscosity, viscoelasticity) and physicochemical (pH, surface tension, conductivity) properties of three commercially available saliva formulations. Upon the addition of NPs (20 µg/mL), antibacterial activity of artificial saliva was found to increase against tested microorganisms by 20% to 50%. NPs, especially gold-coated ones, decrease the adhesion of Gram-positive and fungal cells by 65% and Gram-negative bacteria cells by 45%. Moreover, the addition of NPs strengthened the antimicrobial properties of tested artificial saliva, without influencing their rheological and physicochemical properties, which stay within the range characterizing the natural saliva collected from healthy subjects.pl
    dc.description.sponsorshipThe study was sponsored by a grant from the Polpharma Scientific Foundation (Katarzyna Niemirowicz-Laskowska).pl
    dc.language.isoenpl
    dc.publisherMDPIpl
    dc.rightsUznanie autorstwa 4.0 Międzynarodowe*
    dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
    dc.subjectsalivapl
    dc.subjectmagnetic nanoparticlespl
    dc.subjectantimicrobialpl
    dc.subjectbiofilmpl
    dc.subjectnanomedicinepl
    dc.titleAntimicrobial and Physicochemical Properties of Artificial Saliva Formulations Supplemented with Core-Shell Magnetic Nanoparticlespl
    dc.typeArticlepl
    dc.rights.holder© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).pl
    dc.identifier.doi10.3390/ijms21061979-
    dc.description.EmailKatarzyna Niemirowicz-Laskowska: katia146@wp.plpl
    dc.description.EmailJoanna Mystkowska: j.mystkowska@pb.edu.plpl
    dc.description.EmailDawid Łysik: d.lysik@pb.edu.plpl
    dc.description.EmailSylwia Chmielewska: sylwia.chmielewska@umb.edu.plpl
    dc.description.EmailGrażyna Tokajuk: grazyna.t1@gmail.compl
    dc.description.EmailIwona Misztalewska-Turkowicz: i.misztalewska@uwb.edu.plpl
    dc.description.EmailAgnieszka Z. Wilczewska: agawilczuwb@gmail.compl
    dc.description.EmailRobert Bucki: buckirobert@gmail.compl
    dc.description.AffiliationKatarzyna Niemirowicz-Laskowska - Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystokpl
    dc.description.AffiliationJoanna Mystkowska - Institute of Biomedical Engineering, Bialystok University of Technologypl
    dc.description.AffiliationDawid Łysik - Institute of Biomedical Engineering, Bialystok University of Technologypl
    dc.description.AffiliationSylwia Chmielewska - Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystokpl
    dc.description.AffiliationGrażyna Tokajuk - Department of Integrated Dentistry, Medical University of Bialystokpl
    dc.description.AffiliationIwona Misztalewska-Turkowicz - Faculty of Chemistry, University of Białystokpl
    dc.description.AffiliationAgnieszka Z. Wilczewska - Faculty of Chemistry, University of Białystokpl
    dc.description.AffiliationRobert Bucki - Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok; Department of Microbiology and Immunology, The Faculty of Medicine and Health Sciences of the Jan Kochanowski University in Kielcepl
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    dc.description.volume21pl
    dc.description.issue6pl
    dc.description.firstpage1pl
    dc.description.lastpage17pl
    dc.identifier.citation2International Journal of Molecular Sciencespl
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    dc.identifier.orcid0000-0002-3386-146X-
    dc.identifier.orcid0000-0002-5370-0030-
    dc.identifier.orcidbrakorcid-
    dc.identifier.orcidbrakorcid-
    dc.identifier.orcidbrakorcid-
    dc.identifier.orcidbrakorcid-
    dc.identifier.orcid0000-0001-7664-9226-
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